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Small Mammals

  • Diphenhydramine is given by mouth or as an injection and is used on and off label to treat allergic reactions, motion sickness, and to induce sedation. Side effects include sleepiness, and less commonly dry mouth and gastrointestinal upset.

  • Common conditions of pet ferrets include diarrhea, intestinal foreign bodies, parasites, heart disease, and various tumors. This handout outlines the causes, clinical signs, and treatment options for each of these conditions. Any variation from normal should be a cause for concern and should be immediately evaluated by your veterinarian.

  • Common conditions of pet rabbits include upper respiratory tract infections, internal and external parasites, dental disease, E. cuniculi infection, gastrointestinal stasis, uterine problems, and pododermatitis (sore hocks). This article discusses causes, signs, and treatments for these conditions. Regular yearly check-ups enable an early diagnosis and treatment of some rabbit diseases. Whenever a rabbit stops eating, for whatever reason, it is important to take them to see your veterinarian immediately for an evaluation.

  • Common conditions of pet rodents include respiratory diseases, gastrointestinal problems, dental problems, and cancer. Diseases of the skin may cause itching, hair loss or flaky skin in rodents. All rodents have teeth that grow continuously throughout their lives. Occasionally, these teeth grow too long and cut into the gums, causing pain when eating. Cancer is often seen in pet rodents, especially mammary (breast) tumors in rats and mice. Rodents with signs of respiratory or GI disease or evidence of a tumor should be seen by a veterinarian who can properly diagnose and treat the underlying condition.

  • Doxycycline is an antibiotic given by mouth in the form of a tablet, capsule, or liquid, used off label to treat certain infections. Common side effects include stomach upset, sun sensitivity, and increases in liver enzymes. Serious side effects include liver failure, seizures, and trouble swallowing. Do not use in pregnant pets and use cautiously in pets with liver disease or in young pets. If a negative reaction occurs, please call your veterinary office.

  • Ear cleansing/drying products are used over-the-counter to treat and prevent ear infections in many species of pets. They come as a liquid solution that is used topically within the ear canal and are typically used in the ears after debris and wax have been removed using a cerumenolytic cleanser.

  • The ear mite is a surface mite that lives on cats, dogs, rabbits, and ferrets. It is usually found in the ear canal but it can also live on the skin surface. Mites are barely visible to the naked eye. Clinical signs of infestation vary in severity and may include ear irritation, leading to scratching at the ears or head shaking, dark waxy or crusty discharge from the ear, areas of hair loss resulting from self-trauma, a crusted rash around or in the ear, and an aural hematoma. Your veterinarian will advise you about which insecticidal products are suitable. Your veterinarian may want to re-examine your pet to ensure that the mites have been eliminated after the initial treatment has been performed.

  • Enalapril is used on and off label and is given by mouth or injection to treat heart failure, high blood pressure, chronic kidney disease, or proteinuria. Common side effects include loss of appetite, vomiting, diarrhea, and tiredness. Do not use in pets that are allergic to it, have an acute kidney injury, or have certain heart conditions.

  • Encephalitozoonsis is a parasitic infection that can affect the kidneys, eyes, and nervous systems of rabbits. Many infected rabbits do not develop clinical signs until they are older or if they become stressed or immunocompromised. Common signs that may develop include heavy white plaques/growths inside one or both eyes, head tilt, eye twitching, and tremors or seizures. Treatments are available, though not all rabbits respond.

  • Enrofloxacin is an antibiotic given by mouth or in the muscle commonly used to treat bacterial infections in cats, dogs, and off label in small mammals, birds, and reptiles. Common side effects include vomiting, diarrhea, and lack of appetite. It should not be used in growing or dehydrated pets, or in cats with kidney disease. Use cautiously in pets with seizures, liver, or kidney disease. If a negative reaction occurs, please call your veterinary office.